MyGastromed

Welcome to MyGastromed, an e-digest service for health professsionals involved in gastroenterology. Each edition contains a round-up of gastro news, views, topics and trends from around the world. If you're looking for education it's in Med-ucation, and for light-hearted observations and anecdotes visit What's up.

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The MyGastromed team.

MyGastromed is provided as a service to health professionals by Takeda.

Update of Plavix® (clopidogrel) label

Due to further study results, changes have been made to the ‘Drug interactions’ section of the US Plavix® (clopidogrel) SPC.“Avoid concomitant use of Plavix with omeprazole or esomeprazole… Consider using another acid-reducing agent with minimal or no CYP2C19 inhibitory effect on the formation of clopidogrel active metabolite. Dexlansoprazole, lansoprazole and pantoprazole had less effect on the antiplatelet activity of Plavix than did omeprazole or esomeprazole.”The Plavix® SPC can be accessed by

IBD: an up-to-date review of current treatment options and epidemiology

Inflammatory Bowel Disease (IBD) is incurable and its incidence is increasing worldwide. Could a better understanding of the epidemiology and natural history of IBD and use of newer medication help achieve better outcomes for these patients?

The effect of polypharmacy and aging on potential drug-drug interactions

Polypharmacy is a major risk factor in drug-drug interactions (DDIs), but is it also influenced by age? A new outpatient study investigates both factors and produces some interesting findings.

Avoiding a poor response to clopidogrel may be achieved through choice of PPI

Clopidogrel has become part of the mainstay of therapy for acute coronary syndromes and in patients post-stenting, but a considerable proportion of patients have a poor response to clopidogrel, leaving them at-risk of thrombotic events. How can concomitant PPI therapy be best managed to help avoid this? A new review offers guidance.1

Antibiotics and inflammatory bowel disease (IBD) development

A Canadian study shows that people diagnosed with IBD are more likely to have been prescribed antibiotics 2-5 years before their diagnosis. What were the key findings of the study which help improve the understanding of IBD development?

Oral manifestations of GERD

A number of studies show a significant association between tooth erosion and gastroesophageal reflux disease (GERD) – something which is also commonly observed by dentists. But just how much of a problem do physicians think it is and what, if anything, should be done?

RefluxReflex Inter-Action game - new version coming soon

A new version of the RefluxReflex Inter-Action game, as seen at UEGW, will be launched at the beginning of June.

UEGW 2011 Review

This year's UEGW meeting in Stockholm was attended by over 12,000 people. Find out what you missed or just relive some of the events.

Reflux Inter-Action – learn PPI interactions interactively

Proton pump inhibitors (PPIs) are used extensively. In practice there appears to be little difference among the PPIs in clinical efficacy at equivalent doses and thus their individual propensities for metabolic drug interactions become important factors to consider in prescribing decisions.Use this fun but comprehensive tool to test out your knowledge. Visit our interactive waiting room and see which patients are suited to which PPI.

Naturally confused about reflux

There’s a wealth of information online about natural approaches to reflux. But some of it is rather more IN-credible than credible.

Professional endorsement or neighbour’s advice: no contest

Despite years of training, healthcare professionals may still find that their advice does not carry the same weight as that of a neighbour, whether virtual or real.

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MyGastromed is provided as a service to health professionals by Takeda.